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Welcome to

Basic Theoretical Research in the Mathematical & Natural Sciences 

THE REUVENI GROUP

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March 26, 2025

Congratulations to Itamar Shitrit!

Congratulations to Itamar Shitrit for winning the outstanding student's scientific achievement award of the center for Physics and Chemistry of living systems at Tel Aviv University. The prize was awarded for his research – Sokoban percolation on the Bethe lattice â€“ which was carried out in collaboration with Ofek Lauber Bonomo.

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February 19, 2025 

Congratulations to Tommer David Keidar!

Congratulations to Tommer David Keidar for winning the outstanding poster award as part of the 88th annual meeting of the Israel Chemical Society. The award was given for his research on the universal linear response of the mean first-passage time.

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January 3, 2025 

New Paper: Queues with service resetting

We develop a comprehensive theory of queueing systems with service resetting, where service times depend on both the server's intrinsic slowdown and the job's inherent size. Analyzing both Poissonian and deterministic resetting policies, we derive conditions under which resetting reduces the mean service time to improve queue performance. Our results, validated through numerical simulations, highlight service resetting as an effective tool for mitigating service time fluctuations in diverse queueing scenarios.

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March 23, 2025

Congratulations to Tommer David Keidar!

Congratulations to Tommer David Keidar for winning the David and Paulina Trotsky Foundation Fellowship for the school year 2024-25.

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January 8, 2025 

New Paper: Accelerating molecular dynamics through informed resetting

We introduce informed stochastic resetting, a novel strategy for enhancing molecular dynamics simulations by selectively resetting only when the reaction coordinate indicates insufficient progress. Applied to a model system and chignolin in explicit water, this approach accelerates Metadynamics simulations by 2–3 orders of magnitude. By leveraging information about reaction progress, informed resetting significantly extends the applicability of stochastic resetting for overcoming time scale limitations in molecular simulations.

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December 9, 2024

New Paper: Inference of non-exponential kinetics through stochastic resetting

We present an inference scheme of long-timescale, non-exponential, kinetics from molecular dynamics simulations accelerated by stochastic resetting. We show that resetting promotes enhanced sampling of the first-passage time distribution at short timescales but often also provides sufficient information to estimate the long-time asymptotics, which allows for kinetics inference. 

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March 20, 2025

New Paper: High-order Michaelis-Menten equations allow inference of hidden kinetic parameters in enzyme catalysis

 

We derive high-order Michaelis-Menten equations that extend the classical linear relation between mean turnover time and reciprocal substrate concentration. These equations reveal universal linear relations for higher-order moments, granting access to previously inaccessible kinetic parameters. We show how key observables—such as the enzyme-substrate lifetime, the binding rate, and the probability of successful catalysis—can all be inferred from these relations.

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January 8, 2025 

New Paper: Smart resetting — An energy-efficient strategy for stochastic search processes

We introduce smart resetting—a strategy that leverages information to selectively reset a diffusing particle only when it benefits its progress toward a target. Our analysis demonstrates that smart resetting consistently lowers the energy cost per mean first passage time compared to regular resetting, achieving the known minimum energy cost bound for a diffusing particle regardless of the resetting rate. We extend our findings to consider nonlinear energetic cost functions and drift-diffusion processes, offering deeper insights into the interplay between information and resetting.

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November 28, 2024

Congratulations to Dr. Yuval Scher!

Congratulations to Dr. Yuval Scher for winning the 2024 Israel Chemical Society, Uri Golik Prize for an Excellent Graduate Student! The prize was awarded for pioneering contributions to chemical kinetics, single-molecule chemistry, and adsorption-desorption dynamics.

Reuveni Group | Tel Aviv University, Tel Aviv 6997801, Israel | Phone: +972-3-640-8694 | Email: shlomire@tauex.tau.ac.il 

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